Acute toxicity (inhalation)

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Term Acute toxicity (inhalation)
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Definition Several groups of experimental animals are exposed for a defined period to the test substance in graduated concentrations, one concentration being used per group. Subsequently observations of effects and deaths are made. Animals which die during the test are necropsied and at the conclusion of the test surviving animals are necropsied.

Animals showing severe and enduring signs of distress and pain may need to be humanely killed. Dosing test substances in a way known to cause marked pain and distress due to corrosive or severe irritating properties need not be carried out.

References 1. http://ecb.jrc.ec.europa.eu/documents/Testing-Methods/ANNEXV/B02web1992.pdf
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