Adverse effect

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Term Adverse effect
Description A biochemical change, functional impairment, or pathologic lesion that affects the performance of the whole organism, or reduces an organism's ability to respond to an additional environmental challenge.
Definition Adverse effect

A biochemical change, functional impairment, or pathologic lesion that affects the performance of the whole organism, or reduces an organism's ability to respond to an additional environmental challenge. Any biochemical change, functional impairment, or pathologic lesion which impairs performance and reduces the ability of an organism to respond to additional challenge. An adverse effect may have different degrees of severity, and should be distinguished from adaptive (beneficial) effects and compensatory (neutral) effects. Change in the morphology, physiology, growth, development, reproduction or life span of an organism, system, or (sub) population that results in an impairment of functional capacity, an impairment of the capacity to compensate for additional stress, or an increase in susceptibility to other influences. change in morphology, physiology, growth, development, or life span of an organism, which results in an impairment of functional capacity, an impairment of the capacity to compensate for additional stress, or an increase in susceptibility to other environmental influences.

References http://www.epa.gov/iris/help_gloss.htm#a
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