Benchmark Response (BMR)

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Term Benchmark Response
Description An adverse effect, used to define a benchmark dose from which an RfD (or RfC) can be developed. The change in response rate over background of the BMR is usually in the range of 5-10%, which is the limit of responses typically observed in well-conducted animal experiments.
Definition Benchmark Response (BMR)

An adverse effect, used to define a benchmark dose from which an RfD (or RfC) can be developed. The change in response rate over background of the BMR is usually in the range of 5-10%, which is the limit of responses typically observed in well-conducted animal experiments.

References http://permanent.access.gpo.gov/lps38234/cfpub.epa.gov/ncea/cfm/bmds.cfm-ActType=default.htm

http://www.epa.gov/iris/help_gloss.htm#a

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